Renoprotective antioxidant effect of alagebrium in experimental diabetes
نویسندگان
چکیده
منابع مشابه
Renoprotective antioxidant effect of alagebrium in experimental diabetes.
BACKGROUND Despite the beneficial effects of alagebrium (ALA), a putative advanced glycation end-product (AGE) breaker, on diabetic nephropathy, its renoprotective mechanisms are incompletely understood. Since oxidative stress exacerbates diabetic renal injury through interaction with AGE, the present study examined the antioxidative property of ALA in db/db mice, mesangial cells cultured under...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2011
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/gfr152